Protein Modification Reagents
Medchemexpress LLC DBCO-PEG4-eosin 5-isothiocyanate | 96.7% | 1228.59 | C50H44Br4N4O11S | 10 MG
DBCO-PEG4-Eosin 5-isothiocyanate is a click-chemistry-enabled fluorescent probe that links a DBCO (dibenzocyclooctyne) reactive group to eosin 5-isothiocyanate via a PEG4 spacer. It is supplied as an orange-red solid for labeling biomolecules using strain-promoted alkyne-azide cycloaddition (SPAAC) and for fluorescence imaging applications.
- Enables copper-free click conjugation via DBCO
- PEG4 spacer improves solubility and reduces steric hindrance
- Eosin 5-isothiocyanate offers red-orange fluorescence for imaging
- High purity suitable for bioconjugation applications
- Supplied in small milligram quantities for research use
- Store sealed, protected from moisture and light; refrigerate for solids
eMolecules 2183440-35-7 | N-(acid-PEG3)-N-bis(PEG3-amine) | Broadpharm571.709 | C25H53N3O11 | 95.000 | NCCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(O)=O | 250mg | 374905433
N-(acid-PEG3)-N-bis(PEG3-amine) | Broadpharm | 2183440-35-7571.709 | C25H53N3O11 | 95.000 | NCCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(O)=O | 250mg | 374905433
![eMolecules 2183440-72-2 | N-(Azido-PEG3)-NH-PEG3-acid HCl salt | Broadpharm422.479 | C17H34N4O8 | 95.000 | OC(=O)CCOCCOCCOCCNCCOCCOCCOCCN=[N+]=[N-] | 250mg | 550804447](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203497.JPG-250.jpg)
eMolecules 2183440-72-2 | N-(Azido-PEG3)-NH-PEG3-acid HCl salt | Broadpharm422.479 | C17H34N4O8 | 95.000 | OC(=O)CCOCCOCCOCCNCCOCCOCCOCCN=[N+]=[N-] | 250mg | 550804447
N-(Azido-PEG3)-NH-PEG3-acid HCl salt | Broadpharm | 2183440-72-2422.479 | C17H34N4O8 | 95.000 | OC(=O)CCOCCOCCOCCNCCOCCOCCOCCN=[N+]=[N-] | 250mg | 550804447
Medchemexpress LLC Boc-NH-PEG4-C2-Boc | 2138484-13-4 | 421.53 | 50 MG
Boc-NH-PEG4-C2-Boc is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound facilitates the development of molecules that leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. It is intended for research use only.
- PEG-based linker structure
- Essential for PROTAC synthesis
- Enables targeted protein degradation via ubiquitin-proteasome system
Medchemexpress LLC DSPE-PEG-NHS | 1445723-73-8 | MFCD03098978 | 80.0% | 5000 (average) | C49H89N2O15P | 25 MG
DSPE-PEG-NHS (average MW 5000) is an NHS-activated PEGylated phospholipid used to functionalize liposomes and nanoparticle platforms. The NHS ester allows covalent attachment to primary amines, while the PEG chain provides steric stabilization and extended circulation, making it useful for targeted and stealth formulations.
- Enables covalent conjugation to amine-containing ligands via NHS-amine chemistry.
- Provides steric stabilization and reduced protein adsorption through PEGylation.
- Amphiphilic structure supports incorporation into lipid bilayers and micelles.
- Available as a solid for convenient handling and storage.
- Typical purity around 80% suitable for formulation development.
Medchemexpress LLC T-Boc-N-amido-PEG5-tosylate | 1404111-69-8 | MFCD34596623 | 96.0% | 491.60 g/mol | C22H37NO9S | 1 G
A Boc-protected PEG5 tosyl linker for chemical conjugation and linker assembly. The reagent combines a hydrophilic five-unit polyethylene glycol spacer with a tosylate leaving group and a Boc-protected amine, providing improved solubility and enabling nucleophilic substitution for installation of PEG-based linkers in medicinal chemistry and bioconjugation workflows.
- Enhances aqueous solubility via PEG5 spacer.
- Enables nucleophilic substitution through tosylate leaving group.
- Protects primary amine with Boc for selective deprotection.
- Suitable for linker assembly and bioconjugation chemistry.
- Compatible with standard organic synthesis conditions.
Medchemexpress LLC Dspe-m-peg-nhs | MFCD03098978 | 99.4% | 3,400 (average) | 5 MG
DSPE-m-PEG-NHS (average MW 3,400) is a pegylated phospholipid with an NHS-activated ester used to introduce PEG chains onto lipid bilayers and to covalently attach amine-containing ligands. It is supplied as a powder for formulation of liposomes and lipid nanoparticles, including applications in nucleic acid vaccine delivery, and is characterized for use in reproducible nanoparticle preparation.
- Pegylated phospholipid with an NHS-activated ester for amine coupling.
- Suitable for liposome and lipid nanoparticle formulation for targeted delivery.
- Average molecular weight 3,400 Da provides steric stabilization.
- High purity for reproducible formulation performance.
- Powder form with recommended freezer storage for long-term stability.
Medchemexpress LLC 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-N-azide | 2839508-98-2 | 96.4% | 831.11 g/mol | C43H83N4O9P | 5 MG
DSPE-N3 is an azide-functionalized distearoyl phosphoethanolamine used as a click-chemistry lipid for bioconjugation and nanoparticle formulation. The amphiphilic molecule presents an azide headgroup that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) to attach alkyne-containing probes, polymers, or targeting ligands, and is commonly applied in liposome and micelle formation, surface functionalization, and targeted delivery research.
- Contains an azide functional group for bioorthogonal click chemistry
- Amphiphilic structure supports liposome and micelle formation
- Suitable for conjugation of alkyne-bearing molecules via CuAAC
- High chemical purity for research-grade applications
- Store sealed at 4°C and protect from moisture for stability
- Available in small lab-scale quantities for formulation work
Worthington Biochemical Corporation TPCK TREAT. TRYPSIN 500MG
A chromatographically purified, diafiltered, lyophilized powder that has been treated with L-(tosylamido-2-phenyl) ethyl chloromethyl ketone (TPCK) to inhibit contaminating chymotryptic activity [Kostka and Carpenter, J. Biol. Chem. 239, 1799 (1964)].
Research Products International Corp Guanidine Hydrochloride, 500 Grams
Protein denaturant used for purifying proteins and nucleic acids.
eMolecules 186020-66-6 | Hydroxy-PEG3-t-butyl ester | Broadpharm | MFCD03791106 | 278.345 | C13H26O6 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCO | 5g | 112541344
Hydroxy-PEG3-t-butyl ester | Broadpharm | 186020-66-6 | MFCD03791106 | 278.345 | C13H26O6 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCO | 5g | 112541344
![eMolecules 940005-81-2 | Bromoacetamido-PEG3-azide | Broadpharm | MFCD22683302 | 339.190 | C10H19BrN4O4 | 0.000 | BrCC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 1g | 200183383](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502202985.JPG-250.jpg)
eMolecules 940005-81-2 | Bromoacetamido-PEG3-azide | Broadpharm | MFCD22683302 | 339.190 | C10H19BrN4O4 | 0.000 | BrCC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 1g | 200183383
Bromoacetamido-PEG3-azide | Broadpharm | 940005-81-2 | MFCD22683302 | 339.190 | C10H19BrN4O4 | 0.000 | BrCC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 1g | 200183383